docs(gamma): add publication-ready secret-gist writeup (RuView + RuVector)

SEO-optimized, plain-English gist for RuView Gamma referencing the RuView and
RuVector projects and branch claude/ruview-beyond-sota-xgv8aq: intro, how it
works, supporting research with honest limits, usage (Rust + ESP32), cautions,
advanced usages (trials/sham/cohort/HIL), credits, and an SEO FAQ. Includes
the gh/curl commands to publish it as a SECRET gist with the user's own token
(no token committed).

https://claude.ai/code/session_01MjBucx95K4BuUxZi8NWwRH
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<!--
Publication-ready GitHub Gist. Publish as a SECRET gist with your own token:
gh gist create --desc "RuView Gamma — adaptive sensory neuromodulation" \
docs/research/ruview-beyond-sota/GAMMA-GIST.md
# (omit --public for a secret/unlisted gist; gh uses your stored PAT/token)
Or with curl + a fine-grained PAT that has the "gists" scope:
curl -H "Authorization: Bearer $GH_TOKEN" \
-X POST https://api.github.com/gists \
-d '{"public":false,"files":{"ruview-gamma.md":{"content":"...">}}}'
Do NOT paste the token into this file or any committed file.
SEO meta description (use as the gist description):
"RuView Gamma: an open, governed engine for adaptive 40 Hz light-and-sound
neuromodulation — personalized entrainment with proof discipline, built on
RuView WiFi sensing and RuVector learning. Research platform, not a medical
device."
-->
# RuView Gamma — Adaptive Sensory Neuromodulation, Done Honestly
> **TL;DR** — RuView Gamma is the open-source **control brain** for an adaptive
> light-and-sound (40 Hz "gamma") neuromodulation device. It personalizes the
> stimulation to each person, watches the body as feedback, learns what works,
> and **refuses to advertise any benefit it hasn't measured**. The most valuable
> thing here is not 40 Hz — it is a governed personalization engine that won't
> overpromise.
>
> **Not a medical device. Not medical advice.** It is a research and engineering
> platform. It makes no Alzheimer's, disease, or treatment claims.
**Keywords:** gamma entrainment, 40 Hz stimulation, GENUS, sensory
neuromodulation, WiFi sensing, adaptive personalization, Bayesian optimization,
Rust, ESP32, digital therapeutics infrastructure, RuView, RuVector.
**Projects:** [RuView](https://github.com/ruvnet/ruview) ·
RuVector (vector learning / response modeling) ·
Branch: `claude/ruview-beyond-sota-xgv8aq` ·
Crate: `v2/crates/ruview-gamma` · Firmware: `firmware/esp32-gamma-stim` ·
Decision record: `docs/adr/ADR-250-adaptive-gamma-entrainment.md`.
---
## 1. The easy introduction
Research from MIT and others (the "GENUS" line of work) found that sitting in
front of a light flickering ~40 times per second, with a matching pulsing
sound, can drive a brain rhythm called **gamma** — studied for Alzheimer's,
post-stroke recovery, sleep, focus, and mood.
Today's devices play a **fixed 40 Hz to everyone**. But brains differ: your best
frequency might be 38.5, 41.2, or somewhere else, and it changes with how calm,
tired, or restless you are. There's no off-the-shelf software that personalizes
this **safely and provably**.
RuView Gamma is that software. Four parts work together:
| Part | Role | Plain-English job |
|------|------|-------------------|
| **The device** | Actuator | Plays the light + sound |
| **RuView** | Sensing | Reads the body as feedback (breathing, stillness, restlessness) over WiFi — no camera, no wearable |
| **RuVector** | Learning | Builds a personal "response map" across sessions |
| **RuFlo** | Governance | Safety stops, tamper-evident audit log, and the claim boundary |
The thesis in one line: **RuView turns the body into the feedback signal,
RuVector turns repeated sessions into a personal response map, the device is the
actuator, and RuFlo makes the whole loop governed, measurable, and auditable.**
---
## 2. How it works
```
enroll (consent + epilepsy/photosensitivity screen)
→ start from 40 Hz prior
→ play a short calibration sweep (3644 Hz)
→ RuView reads body state each session
→ score "safe entrainment" (not raw gamma)
→ RuVector updates the personal response map
→ Bayesian optimizer recommends the next best safe setting
→ every session is witness-hashed into a tamper-evident log
```
Key design choices that make it trustworthy:
- **40 Hz is a starting guess, not the answer.** A Gaussian-process optimizer
searches the safe 3644 Hz band for *your* peak — and proves it can recover a
known peak within ±1 Hz in tests.
- **Safety is a hard gate, not a weighted preference.** A latched safety monitor
stops on adverse symptoms, a stop request, or low sensor confidence — in about
**9 nanoseconds** per check — and once it fires, the session **cannot silently
resume**.
- **A compiled-in safety envelope** (3644 Hz, capped brightness/volume/
duration) bounds everything. The optimizer can never widen it.
- **Cross-person warm-start without identity.** A new user can be seeded from
anonymized, one-way-hashed profiles of similar responders — but borrowed
expectations are **down-weighted** and never counted as your measured data.
- **Tamper-evident proof.** Every session produces a SHA-256 witness over
exactly what was played and sensed. Re-running the same inputs reproduces the
identical hash — a regulator, clinician, or trial auditor can verify nothing
was fudged. The pinned reference witness is `13cb164c…`.
### The hard claim gate (the important part)
A program may surface a benefit claim **only** if all four pass:
```
claim_allowed = entrainment_pass AND safety_pass
AND adherence_pass AND repeatability_pass
```
Anything less returns `research use only — no claim`. The marketing claim is
literally unreadable in the code except through this gate.
### It's a platform, not one gadget
Seven programs ship, each with its own safety envelope, objective, state-gating,
evidence level, and a single non-disease claim:
| Program | Evidence | What it tunes for |
|---------|----------|-------------------|
| Alzheimer's research | medium preclinical / early human | entrainment + trial monitoring |
| Post-stroke cognition | early human | gentle, recovery-state tracking |
| Sleep optimization | early/plausible | audio-only, near-dark, timed to sleep state |
| Attention / working memory | mixed | personal frequency discovery |
| Mood / arousal | early human | calming response, avoid overstimulation |
| Home wellness | speculative | safe personalization, no treatment claim |
| Drug + device trial infra | strong (as infrastructure) | governed, reproducible measurement |
---
## 3. Research supporting it (and its honest limits)
- **Preclinical (strongest):** a 2024 *Nature* paper showed 40 Hz multisensory
stimulation promoted cerebrospinal-fluid influx and amyloid clearance via the
glymphatic system in Alzheimer's-model mice; blocking that clearance abolished
the effect.
- **Early human:** a 2022 study found 40 Hz sensory stimulation feasible and
well-tolerated in mild Alzheimer's, with exploratory signals on structure,
connectivity, sleep, and memory. A small 2025 two-year pilot reported safety
and feasibility, but the sample was tiny and not definitive.
- **Frequency is not one-size-fits-all:** a 2025 *PLOS One* study re-evaluated
gamma frequency across 3644 Hz — direct motivation for *measuring* the
individual's frequency rather than assuming 40 Hz.
- **Adjacent areas (early/mixed):** post-stroke cognition, sleep (40 Hz evoked
without degrading sleep), attention/working-memory (mixed, protocol-dependent),
and mood/arousal.
**Honest limits, encoded as non-goals:** RF sensing does not measure amyloid;
personalized frequency improving clinical outcomes is unproven; consumer use
without screening is not safe; 40 Hz is not always optimal. The software makes
none of these claims.
---
## 4. How to use it
### Run the governed engine (Rust)
```bash
git clone https://github.com/ruvnet/ruview
cd ruview && git checkout claude/ruview-beyond-sota-xgv8aq
cd v2
cargo test -p ruview-gamma --no-default-features # 97 tests + 1 doctest
cargo bench -p ruview-gamma --no-default-features # criterion micro-benchmarks
```
```rust
use ruview_gamma::{
ruflo::{Consent, RufloGovernor},
program::NeuroProgram,
response::RuViewState,
simulator::{LatentPerson, ResponseSimulator},
stimulus::StimulusParameters,
};
let mut gov = RufloGovernor::enroll_program(
"subject-001", NeuroProgram::sleep_optimization(), &[], Consent::Granted,
).expect("cleared to participate");
let sim = ResponseSimulator::new(42); // deterministic stand-in for hardware
let latent = LatentPerson::from_id("subject-001");
let state = RuViewState::calm_baseline();
gov.run_calibration(&sim, &latent, &state, 5.0, 0).unwrap();
let rec = gov.recommend(&gov.prior()); // always inside the safety envelope
```
### Run the device (ESP32)
```bash
cd firmware/esp32-gamma-stim
# Host-side safety-core tests — no hardware, no ESP-IDF:
gcc -Wall -Wextra -Werror -O2 -I main tests/test_stim_core.c main/stim_core.c -o /tmp/t && /tmp/t
# On hardware (ESP-IDF v5.2+):
idf.py set-target esp32s3 && idf.py build flash monitor
```
Serial protocol (frequency in millihertz, so 40.0 Hz = `40000`):
```
START 40000 30 28 600 # 40 Hz, 30% brightness, 28% volume, 10 min
STOP | STATUS | UNLOCK | VERSION
```
### Benchmarks (indicative)
| Path | Time | Role |
|------|------|------|
| Safety tick | ~8 ns | real-time stop path |
| Recommendation | ~15 µs | per-session decision |
| Cohort kNN (500 profiles) | ~15 µs | warm-start matching |
| Calibration sweep | ~115 µs | setup/tuning |
| Full acceptance grading | ~425 µs | enrollment only |
---
## 5. Cautions (read these)
- ⚠️ **Flicker can trigger seizures.** Epilepsy and photosensitivity are **hard
exclusions** in software; a hardware e-stop is mandatory for any human-facing
run. Migraine/psychiatric instability/implanted neuro devices require
clinical supervision.
- ⚠️ **Not a treatment.** No Alzheimer's/disease/efficacy claim. The only
product claim is "personalized entrainment optimization," and even that is
gated behind measured entrainment + safety + adherence + repeatability.
- ⚠️ **No hardware actuation in the core crate.** The Rust crate is a validated
decision/safety/learning/audit engine tested against a simulator; the ESP32
firmware is the actuator. Real EEG validation is a separate, deferred step.
- ⚠️ **Optical safety is the integrator's job.** The firmware caps PWM duty, but
absolute luminance/eye-safety belongs to the LED driver and optical design.
- ⚠️ **Research/IRB context required** for any study with human subjects,
especially clinical populations.
---
## 6. Advanced usages
- **Drug + device trials (strongest near-term use):** use RuFlo as the governed
measurement layer — consent, inclusion/exclusion, **sham/blinding**, per-session
witness hashes, and clinician export — to make *someone else's* therapy trial
auditable and reproducible. The value is the instrument, not a therapy claim.
- **Sham-controlled studies:** `TrialMode::Sham` logs the participant-facing
protocol while delivering no entrainment, for blinded arms.
- **Cohort transfer learning:** export anonymized response profiles and
warm-start new participants via RuVector kNN — privacy-preserving, one-way
hashed, never identity-bearing.
- **Drift-triggered recalibration:** a Welford-centroid drift detector flags when
a person's physiology has shifted enough to warrant re-running calibration.
- **Hardware-in-the-loop acceptance:** capture LED frequency, A/V sync, and stop
latency on the bench and grade them with `hil::verify_hil` against fixed
targets (±0.1 Hz, <5 ms, <100 ms, 100% hash reproducibility, ≥20% EEG lift).
- **Edge deployment:** the engine is dependency-light and deterministic; an HNSW
(RuVector) backend drops in for cohort search past ~10⁵ profiles.
---
## 7. Credits
- **RuView** — WiFi/RF human sensing platform that supplies the passive body
feedback signal. https://github.com/ruvnet/ruview
- **RuVector** — vector learning / response-curve modeling (cohort warm-start,
drift detection, clustering; HNSW-ready).
- **RuFlo** — governance, audit, consent, and protocol execution layer.
- Built by the RuView contributors on branch
`claude/ruview-beyond-sota-xgv8aq`. Decision record: ADR-250.
- Scientific inspiration: the GENUS / 40 Hz gamma-entrainment research community
(MIT Tsai/Boyden labs and others). This project implements *engineering and
governance*, not their clinical findings.
---
## 8. FAQ (SEO)
**What is gamma entrainment?** Driving ~40 Hz brain rhythms with rhythmic light
and/or sound. RuView Gamma personalizes the exact frequency per person.
**Is RuView Gamma a medical device?** No. It is an open research and engineering
platform that makes no treatment or disease claims.
**Does it cure or treat Alzheimer's?** No. It optimizes and audits stimulation
protocols; clinical outcomes are explicitly out of scope.
**Can I run it on an ESP32?** Yes — `firmware/esp32-gamma-stim` drives the LED +
audio flicker with a hardware emergency stop and a compiled-in safety envelope.
**Why is it "honest"?** A program's benefit claim is unreadable in code until it
passes measured entrainment, safety, adherence, and repeatability.
**License / source:** see the RuView repository, branch
`claude/ruview-beyond-sota-xgv8aq`.
---
*RuView Gamma — personalized neural-rhythm optimization with tamper-evident
proof. Not a medical claim. Not a consumer miracle device. A tested, safety-first
engine ready for hardware, EEG validation, and serious clinical research.*